What is the catalog number for CD54 Antibody / ICAM-1?

The catalog number for CD54 Antibody / ICAM-1 is V4611-20UG.

What sizes are available for CD54 Antibody / ICAM-1?

CD54 Antibody / ICAM-1 is available in the following size(s): 20 µg.

Is CD54 Antibody / ICAM-1 in stock?

CD54 Antibody / ICAM-1 is currently made to order / not held in immediate stock. Contact us for lead time.

CD54 Antibody / ICAM-1

Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) . It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1) . This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P05362

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant fragment corresponding to the intracellular portion of the human protein was used as the immunogen for the CD54 antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

ICAM1/8247R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the CD54 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD54 antibody is available for research use only.

Storage Conditions

Aliquot the CD54 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the CD54 antibody should be determined by the researcher.

Location

Cell Surface

Image Legend

IHC staining of FFPE human tonsil tissue with CD54 / ICAM-1 antibody (clone ICAM1/8247R) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.