HAb18G Antibody / CD147 / Emmprin / Basigin

HAb18G, also called CD147, is expressed more intensely on thymocytes than on mature peripheral blood T cells. It is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA (Order BSA-free format for coating), Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

P35613

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human protein was used as the immunogen for the HAb18G antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

BSG/7957

Applications

ELISA, IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the HAb18G antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HAb18G antibody is available for research use only.

Storage Conditions

Aliquot the HAb18G antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the HAb18G antibody should be determined by the researcher.

Location

Cell surface

Image Legend

IHC staining of FFPE human renal cell carcinoma tissue with HAb18G antibody (clone BSG/7957) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.