CD79b Antibody
CD79 (also designated Ig Alpha/Ig beta) is a heterodimer composed of Alpha chains, designated CD79A or MB-1, and beta chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
Product Specifications
UniProt
P40259
Host
Mouse
Immunogen
A recombinant fragment of human CD79b protein was used as the immunogen for the CD79b antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
ELISA, IHC-P
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CD79b antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD79b antibody is available for research use only.
Product Datasheet
https://cdn.gentaur.com/products/800/50551498/datasheet/v4533-20ug.pdf
CAS Number
9007-83-4
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