CCL18 Antibody / PARC

Chemokines are members of a superfamily of small inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP) -1a, MIP-1b, MIP-2, MIP-3a, MIP-3b, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. MIP-4 is constituitively expressed in several normal tissues and is highly expressed in plasma.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

P55774

Host

Mouse

Reactivity

Human

Immunogen

A recombinant partial protein sequence (within amino acids 1-89) from the human protein was used as the immunogen for the CCL18 antibody.

Clonality

Monoclonal

Isotype

IgG

Clone

CCL18/3744

Applications

IHC-P

Purity

Protein A affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the CCL18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CCL18 antibody is available for research use only.

Storage Conditions

Aliquot the CCL18 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the CCL18 antibody should be determined by the researcher.

Location

Secreted

Image Legend

IHC staining of FFPE human adrenal gland tissue with CCL18 antibody (clone CCL18/3744) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.