TUBB3 Antibody / Beta Tubulin
This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation.
Product Specifications
CAS Number
9000-83-3
Specifications
Western blot: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q13509
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 250-450) from the human protein was used as the immunogen for the TUBB3 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RTUBB3/7406
Type
Recombinant
Applications
WB, IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the TUBB3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TUBB3 antibody is available for research use only.
Storage Conditions
Aliquot the TUBB3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the TUBB3 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of human PC3 cell lysate with TUBB3 antibody (clone rTUBB3/7406) . Predicted molecular weight ~50 kDa.
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