Recombinant MSLN Antibody / Mesothelin
Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT, Western blot: 2-4 µg/mL
UniProt
Q13421
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Recombinant Monoclonal
Isotype
IgG2b κ
Clone
RMSLN/8764
Type
Recombinant
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant MSLN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant MSLN antibody is available for research use only.
Storage Conditions
Aliquot the recombinant MSLN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant MSLN antibody should be determined by the researcher.
Location
Cell Surface, Secreted
Image Legend
Western blot testing of human OVCAR-3 cell lysate with MSLN antibody. Predicted molecular weight ~70 kDa (precursor), ~40 kDa (processed form) .
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