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Recombinant Mesothelin Antibody / MSLN

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Product Specifications

CAS Number

9000-83-3

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

Q13421

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant partial protein sequence (within amino acids 273-407) from the human protein was used as the immunogen for the recombinant Mesothelin antibody.

Clonality

Recombinant Monoclonal

Isotype

IgG κ

Clone

MSLN/6443R

Type

Recombinant

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the recombinant Mesothelin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This recombinant Mesothelin antibody is available for research use only.

Storage Conditions

Aliquot the recombinant Mesothelin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the recombinant Mesothelin antibody should be determined by the researcher.

Location

Cell surface, Secreted

Image Legend

SDS-PAGE analysis of purified, BSA-free recombinant Mesothelin antibody (clone MSLN/6443R) as confirmation of integrity and purity.

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