GFRP Antibody / GCHFR
GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P30047
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment of human protein was used as the immunogen for the GCHFR antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
GCHFR/7731
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the GFRP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GFRP antibody is available for research use only.
Storage Conditions
Aliquot the GFRP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the GFRP antibody should be determined by the researcher.
Location
Cytoplasm (Lysosome)
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human IL-1RAcP/IL1R3 Protein (His Tag)
Recombinant Human IL-1RAcP/IL1R3 Protein (His Tag)
Z DNA binding protein (ZBP1) (NM_001160418) Human Over-expression Lysate
RNF89 (TRIM6) (NM_058166) Human Over-expression Lysate
