Recombinant LGALS3 Antibody / Galectin-3
Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms. Galectin-3 may also be useful in the identification of certain liver disorders.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 2-4 µg/mL
UniProt
P17931
Host
Mouse
Reactivity
Human
Immunogen
A recombinant fragment from the human protein was used as the immunogen for the recombinant LGALS3 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG1 k
Clone
RLGALS3/7286
Type
Recombinant
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the recombinant LGALS3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This recombinant LGALS3 antibody is available for research use only.
Storage Conditions
Aliquot the recombinant LGALS3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the recombinant LGALS3 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Western blot testing of human MCF7 cell lysate with recombinant LGALS3 antibody (clone rLGALS3/7286) . Predicted molecular weight ~26 kDa.
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