Galectin-3 Antibody / LGALS3
Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms. Galectin-3 may also be useful in the identification of certain liver disorders.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT, Western blot: 2-4 µg/mL
UniProt
P17931
Host
Mouse
Reactivity
Human
Immunogen
A portin of amino acids 150-200 from the human protein was used as the immunogen for the Galectin-3 antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
LGALS3/6583
Applications
IHC-P, WB
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Galectin-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Galectin-3 antibody is available for research use only.
Storage Conditions
Aliquot the Galectin-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Galectin-3 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
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