CD162 Antibody / PSGL-1
CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q14242
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the CD162 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
PSGL1/8135R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the CD162 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD162 antibody is available for research use only.
Storage Conditions
Aliquot the CD162 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the CD162 antibody should be determined by the researcher.
Location
Cell surface
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
![Macrophage Scavenger Receptor I (MSR1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1F10]](https://cdn.genprice.uk/products/937/68dd1b78061270361ea1b395/imageurl/ta802781bm.webp)
Macrophage Scavenger Receptor I (MSR1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1F10]
CNTF Receptor alpha (CNTFR) (NM_001842) Human Over-expression Lysate
