Cytokeratin 5/6 Antibody
Cytokeratin 5 is a basic protein that is closely related to Cytokeratin 6. They share similar tissue distribution and are found in various proportions in many non-keratinizing stratified squamous epithelia eg. tongue mucosa, as well as in basal epithelia of trachea, basal cells of epidermis, hair follicles, sebaceous and sweat glands of skin, luminal cells of the mammary gland, basal cells of prostate, urothelium, vagina and endocervical mucosa. Cytokeratins 5 and 6 are also expressed in basal cell epitheliomas, squamous cell carcinomas of skin, tongue, epiglottis and of the rectal-anal region. Cytokeratin 5/6 mAb is a useful aid for classification of epithelioid mesotheliomas.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P13647, P02538
Host
Rabbit
Reactivity
Human
Immunogen
Human Cytokeratin 5- and Cytokeratin 6-homologous recombinant protein fragments were used as the immunogen for the Cytokeratin 5/6 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
KRT5.6/8275R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Cytokeratin 5/6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Cytokeratin 5/6 antibody is available for research use only.
Storage Conditions
Aliquot the Cytokeratin 5/6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Cytokeratin 5/6 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Documents
Frequently Asked Questions
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