Cytokeratin 1 Antibody / CK1 / KRT1
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8) . Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10) . Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P04264
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant full-length human protein was used as the immunogen for the Cytokeratin 1 antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
KRT1/8342R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Cytokeratin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Cytokeratin 1 antibody is available for research use only.
Storage Conditions
Aliquot the Cytokeratin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Cytokeratin 1 antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Cytokeratin 17 (E3), CF740 conjugate, 0.1mg/mL
CD63 (MX-49.129.5), CF488A conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF594 conjugate, 0.1mg/mL
CD81 / TAPA-1 (1.3.3.22), CF405S conjugate, 0.1mg/mL
P21 / WAF1 (WA-1), CF568 conjugate, 0.1mg/mL
