CD63 Antibody / LAMP-3
CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
P08962
Host
Mouse
Reactivity
Human
Immunogen
A recombinant partial protein sequence (within amino acids 100-200) from the human protein was used as the immunogen for the CD63 antibody.
Clonality
Monoclonal
Isotype
IgG2 κ
Clone
LAMP3/7369
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Aliquot the CD63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD63 antibody is available for research use only.
Storage Conditions
Aliquot the CD63 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Optimal dilution of the CD63 antibody should be determined by the researcher.
Location
Cell surface, Cytoplasm
Image Legend
Documents
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human Ammonium transporter Rh type A (RHAG), partial, Biotinylated
Recombinant Human Ammonium transporter Rh type A (RHAG), partial, Biotinylated
Recombinant Human Ammonium transporter Rh type A (RHAG), partial, Biotinylated
Phospho-DOK2 (Tyr142) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated