Mammaglobin Antibody
Mammaglobin, 10 kDa, is a cytoplasmic protein, a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been reported positive, usually only focally. Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
Product Specifications
CAS Number
9000-83-3
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT
UniProt
Q13296
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant fragment of human Mammaglobin/SCGB2A2 protein was used as the immunogen for the Mammaglobin antibody.
Clonality
Recombinant Monoclonal
Isotype
IgG κ
Clone
MGB/7980R
Type
Recombinant
Applications
IHC-P
Purity
Protein A/G affinity
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the Mammaglobin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Mammaglobin antibody is available for research use only.
Storage Conditions
Aliquot the Mammaglobin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Mammaglobin antibody should be determined by the researcher.
Location
Cytoplasm
Image Legend
Frequently Asked Questions
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