FSH beta Antibody

Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 minutes at RT

UniProt

P01225

Host

Mouse

Reactivity

Human

Immunogen

A recombinant partial protein (within amino acids 1-100) from the human protein was used as the immunogen for the FSH beta antibody.

Clonality

Monoclonal

Isotype

IgG3 κ

Clone

FSHB/6845

Applications

IHC-P

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the FSH beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FSH beta antibody is available for research use only.

Storage Conditions

Aliquot the FSH beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the FSH beta antibody should be determined by the researcher.

Location

Cytoplasm, Secreted

Image Legend

IHC staining of FFPE human pituitary tissue with FSH beta antibody (clone FSHB/6845) . HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.