SFMBT2 Antibody

The SFMBT2 (Scm-like with four MBT domains 2) gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Sfmbt2 is a Polycomb group (PcG) gene that maps to the proximal region of Chromosome 2, and is a putative imprinted gene. Sfmbt2 is the first imprinted gene within this region to be identified. Studies indicate that six different translocations involving proximal chromosome 2 results in lethality when present as a maternal uniparental duplication.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL

UniProt

Q5VUG0

Host

Mouse

Reactivity

Human

Immunogen

Recombinant full-length human SFMBT2 protein was used as the immunogen for the SFMBT2 antibody.

Clonality

Monoclonal

Isotype

IgG2c

Clone

PCRP-SFMBT2-2E12

Applications

FACS, IF

Purity

Protein A/G affinity

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Reconstitution

Aliquot the SFMBT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SFMBT2 antibody is available for research use only.

Storage Conditions

Aliquot the SFMBT2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Optimal dilution of the SFMBT2 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

Immunofluorescent staining of PFA-fixed human HeLa cells with SFMBT2 antibody (clone PCRP-SFMBT2-2E12) followed by goat anti-mouse IgG-CF488 (green) ; Red = CF640R phalloidin.