FOXP4 Antibody

The FOXP4 (Scm-like with four MBT domains 2) gene shares high similarity with the Drosophila Scm (sex comb on midleg) gene. Sfmbt2 is a Polycomb group (PcG) gene that maps to the proximal region of Chromosome 2, and is a putative imprinted gene. Sfmbt2 is the first imprinted gene within this region to be identified. Studies indicate that six different translocations involving proximal chromosome 2 results in lethality when present as a maternal uniparental duplication.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-2 µg/mL

UniProt

Q8IVH2

Host

Mouse

Reactivity

Human

Immunogen

A recombinant partial protein (within amino acids 302-541) from the human protein was used as the immunogen for the FOXP4 antibody.

Clonality

Monoclonal

Isotype

IgG2c

Clone

PCRP-FOXP4-1G7

Applications

FACS, IF

Purity

Protein A/G affinity

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Aliquot the FOXP4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FOXP4 antibody is available for research use only.

Storage Conditions

Aliquot the FOXP4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Applications Notes

Optimal dilution of the FOXP4 antibody should be determined by the researcher.

Location

Nucleus

Image Legend

Immunofluorescent staining of PFA-fixed human HeLa cells with FOXP4 antibody (clone PCRP-FOXP4-1G7) followed by goat anti-mouse IgG-CF488 (green) . Staining observed in the cytoplasm and nucleus but not nucleoli.