MRPP1 Antibody / NY-REN-49 / TRMT10C

The TRMT10C gene encodes 'tRNA methyltransferase 10 homolog C, ' also called MRPP1 (Mitochondrial ribonuclease P protein 1) and 'Renal carcinoma antigen NY-REN-49, ' the precursor of a subunit of the mitochondrial ribonuclease P, which is involved in 5' processing of mitochondrial tRNAs. The encoded protein may confer RNA-binding capacity to mitochondrial ribonuclease P and may be essential for transcript processing, RNA modification, translation and mitochondrial respiration.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL, Immunofluorescence: 5 µg/mL, Flow cytometry: 1-3ug/million cells, Direct ELISA: 0.1-0.5 µg/mL

UniProt

Q7L0Y3

Host

Rabbit

Reactivity

Human

Immunogen

E. coli-derived recombinant human protein (amino acids L36-K340) was used as the immunogen for the MRPP1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, IHC-P, IF, FACS, Direct ELISA

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the MRPP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This MRPP1 antibody is available for research use only.

Storage Conditions

After reconstitution, the MRPP1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the MRPP1 antibody should be determined by the researcher.

Location

Cytoplasmic (mitochondria), nuclear

Image Legend

IHC staining of FFPE human ovarian cancer tissue with MRPP1 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.