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SEPTIN1 Antibody / SEPT1

Septin-1, also called LARP, is a protein that in humans is encoded by the SEPTIN1 gene. This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Flow cytometry: 1-3ug/million cells

UniProt

Q8WYJ6

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Amino acids RDRASRSKLSRQSATEIPLPML were used as the immunogen for the SEPTIN1 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the SEPTIN1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This SEPTIN1 antibody is available for research use only.

Storage Conditions

After reconstitution, the SEPTIN1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the SEPTIN1 antibody should be determined by the researcher.

Image Legend

Flow cytometry testing of mouse RAW264.7 cells with SEPTIN1 antibody at 1ug/million cells (blocked with goat sera) ; Red=cells alone, Green=isotype control, Blue= LARP antibody.

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