Regulator of Chromosome Condensation Antibody / RCC1 / CHC1
Regulator of Chromosome Condensation, also named RCC1, SNHG3-RCC1 and CHC1 (Chromosome condensation protein 1), promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL
UniProt
P18754
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein (amino acids A14-S421) was used as the immunogen for the Regulator of Chromosome Condensation antibody.
Clonality
Monoclonal
Isotype
IgG1
Clone
7B5D2
Applications
WB
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This Regulator of Chromosome Condensation antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the Regulator of Chromosome Condensation antibody should be determined by the researcher.
Location
Nuclear, cytoplasmic
Image Legend
Documents
Frequently Asked Questions
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