CD51 Antibody / Integrin alpha V / ITGAV / Vitronectin Receptor

Integrin alpha-V / CD51 is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily (cytoadhesins) . The human locus for the av gene (VNRA) was previously mapped to the long arm of chromosome 2. Sims et al. (2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL

UniProt

P06756

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein (amino acids H732-D970) was used as the immunogen for the CD51 antibody.

Clonality

Monoclonal

Isotype

IgG2b

Clone

8B10H2

Applications

WB, IF, IHC-P

Purity

Antigen affinity purified

Format

Antigen affinity purified

Buffer

Lyophilized from 1X PBS with 2% Trehalose

Reconstitution

After reconstitution, the CD51 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Limitations

This CD51 antibody is available for research use only.

Storage Conditions

After reconstitution, the CD51 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Formulation

0.5 mg/mL if reconstituted with 0.2ml sterile DI water

Applications Notes

Optimal dilution of the CD51 antibody should be determined by the researcher.

Image Legend

IHC staining of FFPE human esophageal squamous carcinoma tissue with CD51 antibody. HIER: boil tissue sections in pH8 EDTA for 20 min and allow to cool before testing.