CD51 Antibody / Integrin alpha V / ITGAV / Vitronectin Receptor
Integrin alpha-V / CD51 is a protein that in humans is encoded by the ITGAV gene. It is a member of the beta 3 integrin subfamily (cytoadhesins) . The human locus for the av gene (VNRA) was previously mapped to the long arm of chromosome 2. Sims et al. (2000) localized the VNRA gene to 2q31. The gene contains 30 exons and spans over 93 kb of genomic DNA. It functions as a receptor for a group of proteins that includes vitronectin, fibrinogen, thrombospondin, and von Willebrand factor.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunofluorescence: 5 µg/mL, Immunohistochemistry (FFPE) : 2-5 µg/mL
UniProt
P06756
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein (amino acids H732-D970) was used as the immunogen for the CD51 antibody.
Clonality
Monoclonal
Isotype
IgG2b
Clone
8B10H2
Applications
WB, IF, IHC-P
Purity
Antigen affinity purified
Format
Antigen affinity purified
Buffer
Lyophilized from 1X PBS with 2% Trehalose
Reconstitution
Limitations
This CD51 antibody is available for research use only.
Storage Conditions
Formulation
0.5 mg/mL if reconstituted with 0.2ml sterile DI water
Applications Notes
Optimal dilution of the CD51 antibody should be determined by the researcher.
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Documents
Frequently Asked Questions
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