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Azido-PEG4-alpha-D-mannose

Azido-PEG4-alpha-D-mannose is a PEG linker that combines an azide group with an alpha-D-mannose moiety. Azido-PEG4-alpha-D-mannose is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Azido-PEG4-alpha-D-mannose has the targeting property of mannose, which can accurately deliver drugs to specific cells or tissues to improve the therapeutic effect of drugs[1].

Product Specifications

CAS Number

[1632372-86-1]

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/azido-peg4-alpha-d-mannose.html

Purity

96.24

Solubility

H2O : 250 mg/mL (ultrasonic)

Smiles

O[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@H]1OCCOCCOCCOCCN=[N+]=[N-]

Molecular Formula

C14H27N3O9

Molecular Weight

381.38

References & Citations

[1]Shaodong Zhang, et al. Mimicking biological membranes with programmable glycan ligands self-assembled from amphiphilic Janus glycodendrimers. Angew Chem Int Ed Engl. 2014 Oct 6;53 (41) :10899-903.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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