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Flecainide (acetate) (Standard)

Flecainide (acetate) (Standard) is the analytical standard of Flecainide (acetate) . This product is intended for research and analytical applications. Flecainide acetate (R-818) is a class 1C antiarrhythmic agent especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.

Product Specifications

CAS Number

54143-56-5

Product Name Alternative

R-818 (Standard)

UNSPSC

12352005

Target

Reference Standards; Sodium Channel

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/flecainide-acetate-standard.html

Smiles

O=C(NCC1NCCCC1)C2=CC(OCC(F)(F)F)=CC=C2OCC(F)(F)F.CC(O)=O

Molecular Formula

C19H24F6N2O5

Molecular Weight

474.39

References & Citations

[1]Yamashita T, Nakajima T, Hamada E, 
 Flecainide inhibits the transient outward current in atrial myocytes isolated from the rabbit heart. J Pharmacol Exp Ther. 1995 Jul;274 (1) :315-21.|[2]Desaphy JF, De Luca A, Didonna MP, Different flecainide sensitivity of hNav1.4 channels and myotonic mutants explained by state-dependent block. J Physiol. 2004 Jan 15;554 (Pt 2) :321-34.|[3]Kohli V. Oral flecainide is effective in management of refractory tachycardia in infants. Indian Heart J. 2013 Mar-Apr;65 (2) :168-71.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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