MMP-9-IN-1

MMP-9-IN-1 is a specific matrix metalloproteinase-9 (MMP-9) inhibitor, which selectively target the hemopexin (PEX) domain of MMP-9, but not other MMPs[1].

Product Specifications

CAS Number

[502887-71-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

MMP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mmp-9-in-1.html

Purity

99.82

Solubility

DMSO : 66.67 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(OC(F)F)C=C1)CSC2=NC(CCC)=CC(N2)=O

Molecular Formula

C16H17F2N3O3S

Molecular Weight

369.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Dufour A, et al. Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res. 2011 Jul 15;71 (14) :4977-88.|[2]Alford VM, Kamath A, Ren X, et al. Targeting the Hemopexin-like Domain of Latent Matrix Metalloproteinase-9 (proMMP-9) with a Small Molecule Inhibitor Prevents the Formation of Focal Adhesion Junctions. ACS Chem Biol. 2017;12 (11) :2788-2803.