VEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is a potent VEGFR-2 kinase inhibitor with an IC50 value of 1.24 nM . VEGFR-2-IN-55 has antitumor activity[1].
Product Specifications
UNSPSC
12352005
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr-2-in-55.html
Smiles
O=C(NC1=CC=CC(SC2=CC3=C(C=C2)C(/C=C/C4=NC=CC=C4)=NN3)=C1)CC5=CC=CC=C5F
Molecular Formula
C28H21FN4OS
Molecular Weight
480.56
References & Citations
[1]Zha H, et al. Design, synthesis and biological evaluation of indazole derivatives as VEGFR-2 kinase inhibitors with anti-angiogenic properties. Eur J Med Chem. 2024 Sep 19;279:116889.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Curated Selection
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