VEGFR-2-IN-55

VEGFR-2-IN-55 (Compound 30) is a potent VEGFR-2 kinase inhibitor with an IC50 value of 1.24 nM . VEGFR-2-IN-55 has antitumor activity[1].

Product Specifications

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vegfr-2-in-55.html

Smiles

O=C(NC1=CC=CC(SC2=CC3=C(C=C2)C(/C=C/C4=NC=CC=C4)=NN3)=C1)CC5=CC=CC=C5F

Molecular Formula

C28H21FN4OS

Molecular Weight

480.56

References & Citations

[1]Zha H, et al. Design, synthesis and biological evaluation of indazole derivatives as VEGFR-2 kinase inhibitors with anti-angiogenic properties. Eur J Med Chem. 2024 Sep 19;279:116889.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

VEGFR2/KDR/Flk-1

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