Idactamab
Idactamab (INT-001) is an IgG1-κ antibody with in vivo activity across a spectrum of hematological malignancies. Idactamab can be used for prepare MEDI7247, a potent and specific ADC, targeting ASCT2 (SLC1A5) [1][2].
Product Specifications
CAS Number
2245205-37-0
Product Name Alternative
INT-001
UNSPSC
12352203
Target
Others
Type
Inhibitory Antibodies
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/idactamab.html
Purity
95.00
Solubility
10 mM in DMSO
Smiles
[Idactamab]
Molecular Weight
(146.54 kDa)
References & Citations
[1]Pore N, et al. Discovery and development of MEDI7247, a novel pyrrolobenzodiazepine (PBD) -based antibody drug conjugate targeting ASCT2, for treating hematological cancers[J]. Blood, 2018, 132: 4071.|[2]Monks N R, et al. Abstract LB-295: MEDI7247, a novel pyrrolobenzodiazepine ADC targeting ASCT2 with potent in vivo activity across a spectrum of hematological malignancies[J]. Cancer Research, 2018, 78 (13_Supplement) : LB-295-LB-295.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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