D-Arabinopyranose-13C5
D-Arabinopyranos-13C5 is 13C labeled D-Arabinopyranos. D-Arabinopyranose is a rare aldehyde pentose, and its ring-opened form is D-arabinose (HY-N0059). D-arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082)[2][3][4][5].
Product Specifications
UNSPSC
12352005
Target
AMPK; Bacterial; Isotope-Labeled Compounds; Parasite; PPAR
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Infection; Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/d-arabinose-13c5.html
Purity
99.9
Smiles
O[13CH]1[13C@H]([13C@@H]([13C@@H]([13CH2]O1)O)O)O
Molecular Formula
13C5H10O5
Molecular Weight
155.09
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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