17β-HSD5 inhibitor 1

17β-HSD5 inhibitor 1 (Compound 29) is a potent 17β-HSD5 inhibitor, with an IC50 of 2.9 nM in HEK-293 cells overexpressing human 17β-HSD5[1].

Product Specifications

CAS Number

[243638-37-1]

UNSPSC

12352005

Target

17β-HSD

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Smiles

C[C@@]12[C@]3(CC[C@@]1([H])[C@@]4([H])[C@](C5=CC=CC=C5CC4)([H])CC2)OC(C(C)(CC3)C)=O

Molecular Formula

C24H32O2

Molecular Weight

352.51

References & Citations

[1]Marchais-Oberwinkler S, Henn C, et al. 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol. 2011 May;125 (1-2) :66-82.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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