17β-HSD5 inhibitor 1
Product Specifications
UNSPSC Description
17β-HSD5 inhibitor 1 (Compound 29) is a potent 17β-HSD5 inhibitor, with an IC50 of 2.9 nM in HEK-293 cells overexpressing human 17β-HSD5[1].
Target Antigen
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
C[C@@]12[C@]3(CC[C@@]1([H])[C@@]4([H])[C@](C5=CC=CC=C5CC4)([H])CC2)OC(C(C)(CC3)C)=O
Molecular Weight
352.51
References & Citations
[1]Marchais-Oberwinkler S, Henn C, et al. 17β-Hydroxysteroid dehydrogenases (17β-HSDs) as therapeutic targets: protein structures, functions, and recent progress in inhibitor development. J Steroid Biochem Mol Biol. 2011 May;125(1-2):66-82.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
243638-37-1
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