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C20 Sphingomyelin (d18:1/20:0)

C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM (d18:1/20:0) ) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin -induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.

Product Specifications

CAS Number

121999-68-6

Product Name Alternative

N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM (d18:1/20:0)

UNSPSC

12352211

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/c20-sphingomyelin-d18-1-20-0.html

Smiles

CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O

Molecular Formula

C43H87N2O6P

Molecular Weight

759.13

References & Citations

[1]Hanamatsu, et al. Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults. Nutr. Diabetes 4 (10), e141 (2014) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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