C20 Sphingomyelin (d18:1/20:0)
C20 Sphingomyelin (d18:1/20:0) (N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM (d18:1/20:0) ) is a naturally occurring sphingolipid. C20 Sphingomyelin (d18:1/20:0) levels are upregulated in the hippocampus of streptozotocin (HY-13753) -induced diabetic rats and in human plasma, positively correlating with insulin resistance in obese humans. C20 Sphingomyelin (d18:1/20:0) is also upregulated in the liver of a mouse model of Niemann-Pick C1 disease, a neurodegenerative cholesterol sphingolipid lysosomal storage disorder.
Product Specifications
CAS Number
[121999-68-6]
Product Name Alternative
N-eicosanoyl-D-erythro-Sphingosylphosphorylcholine; SM (d18:1/20:0)
UNSPSC
12352211
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/c20-sphingomyelin-d18-1-20-0.html
Smiles
CCCCCCCCCCCCCCCCCCCC(N[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)COP(OCC[N+](C)(C)C)([O-])=O)=O
Molecular Formula
C43H87N2O6P
Molecular Weight
759.13
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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