WT-TTR inhibitor 1
WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29.05% inhibition at 100 μM[1].
Product Specifications
CAS Number
[23983-05-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Transthyretin (TTR)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/wt-ttr-inhibitor-1.html
Purity
99.67
Solubility
DMSO : 4.76 mg/mL (ultrasonic; warming)
Smiles
O=C1/C(SC2=NC3=C(N21)C=CC=C3)=C/C4=C(Cl)C=CC=C4
Molecular Formula
C16H9ClN2OS
Molecular Weight
312.77
Precautions
H302, H315, H319
References & Citations
[1]Avadhesha Surolia. Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates. Patent US20100190832A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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