NSC682769

NSC682769 is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . NSC682769 can be used for synthesis PROTAC YAP degrader-1 (HY-168016) [1].

Product Specifications

CAS Number

[205048-79-9]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsc682769.html

Smiles

O=C1NC2=CC=CC=C2C3=NC(C4=CC=CC=C4)=CC(C(C=C5OC)=CC=C5OC)=C3C1

Molecular Formula

C27H22N2O3

Molecular Weight

422.48

References & Citations

[1]Zhou C, et al. Exploring Degradation of Intrinsically Disordered Protein Yes-Associated Protein Induced by Proteolysis TArgeting Chimeras. J Med Chem. 2024 Sep 12;67 (17) :15168-15198.