Docusate (Sodium)

Docusate Sodium (Dioctyl sulfosuccinate sodium salt) is one of the main components in stool softeners. Docusate Sodium is a sulfated surfactant and may inactivate viral pathogens by disrupting viral envelopes and/or denaturing/disassociating proteins. Docusate Sodium is effective in vitro against wild type and drug-resistant strains of HSV type 1 and 2. Docusate Sodium is an obesogen. Docusate Sodium with developmental exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipidemia in offspring fed a standard diet in mice[1][2].

Product Specifications

CAS Number

[577-11-7]

Product Name Alternative

Dioctyl sulfosuccinate (sodium salt)

UNSPSC

12352100

Hazard Statement

H315, H318

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Docusate-Sodium.html

Purity

98.0

Solubility

H2O : ≥ 20 mg/mL

Smiles

O=C(OCC(CC)CCCC)C(S(=O)(O[Na])=O)CC(OCC(CC)CCCC)=O

Molecular Formula

C20H37NaO7S

Molecular Weight

444.56

Precautions

H315, H318

References & Citations

[1]Alexis M Temkin, et al. Increased adiposity, inflammation, metabolic disruption and dyslipidemia in adult male offspring of DOSS treated C57BL/6 dams. Sci Rep. 2019 Feb 6;9 (1) :1530.|[2]Y Gong, et al. Preclinical evaluation of docusate as protective agent from herpes simplex viruses. Antiviral Res. 2001 Oct;52 (1) :25-32.