A32390A
A32390A is a dopamine β-hydroxylase inhibitor and copper chelator. A32390A can inhibit the synthesis of norepinephrine, which helps lower blood pressure in DOCA hypertensive rats. A32390A can be used in research on hypertension, bacterial infections, and metabolic disorders[1].
Product Specifications
CAS Number
61241-59-6
UNSPSC
12352211
Target
Bacterial; Dopamine β-hydroxylase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection; Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/a32390a.html
Smiles
O[C@@H]([C@H]([C@@H]([C@@H](COC(/C([N+]#[C-])=C(C)\C)=O)O)O)O)COC(/C([N+]#[C-])=C(C)\C)=O
Molecular Formula
C18H24N2O8
Molecular Weight
396.39
References & Citations
[1]Zhu M, et al. Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition. J Nat Prod. 2020 May 22;83 (5) :1634-1640. |[2]Fuller RW, et al. New inhibitors of dopamine beta-hydroxylase. Adv Enzyme Regul. 1976;15:267-81.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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