Human Claudin-3 Full Length Protein (VLP)

Human Claudin-3 Full Length Protein (VLP) (CL3-H52P3) is expressed from human 293 cells (HEK293) . It contains AA Met 1 - Val 220 (Accession # O15551) .

Product Specifications

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat.

Specifications

This protein .

Accession Number

O15551

Expression Region

Met 1 - Val 220

Host

HEK293

Target

Claudin-3

Conjugation

Unconjugated

Source

Human

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 12 months under sterile conditions.

Bioactivity

Immobilized Human Claudin-3 Full Length Protein (VLP) (Cat. No. CL3-H52P3) at 5 μg/mL (100 μL/well) can bind Anti-Claudin 3 Antibody, Human IgG1 with a linear range of 0.005-0.078 μg/mL (QC tested).

Format

Liquid

Buffer

PBS, Arginine, pH7.4

Additives

Trehalose

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

100ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/CL3-H52P3.pdf

Species