Pomalidomide-PEG2-OMs
Pomalidomide-PEG2-Oms (CRBN ligand Pomalidomide (HY-10984) ) is an E3 Ligase Ligand-Linker Conjugate for EGFR PROTAC DDC-01-163 (HY-139997) [1].
Product Specifications
CAS Number
[2140807-37-8]
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-peg2-oms.html
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOS(=O)(C)=O)=CC=C3)=O)=O
Molecular Formula
C20H25N3O9S
Molecular Weight
483.49
References & Citations
[1]Jaebong Jang, et al. Mutant-Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug-Resistant Mutations. Angew Chem Int Ed Engl. 2020 Aug 17;59 (34) :14481-14489.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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