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Oxatomide (Standard)

Oxatomide (Standard) (KW-4354 (Standard) ) is the analytical standard of Oxatomide. This product is intended for research and analytical applications. Oxatomide (KW-4354) is an orally active dual antagonist of the H1-histamine receptor and the P2X7 receptor, as well as an inhibitor of serotonin. Oxatomide possesses antihistaminic, antiallergic and anti-inflammatory activities. Oxatomide can be used in the research of allergic diseases[1][2].

Product Specifications

CAS Number

60607-34-3

Product Name Alternative

KW-4354 (Standard)

UNSPSC

12352005

Target

5-HT Receptor; Apoptosis; COX; Histamine Receptor; P2X Receptor; p38 MAPK; PERK; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; GPCR/G Protein; Immunology/Inflammation; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/oxatomide-standard.html

Smiles

O=C1NC2=CC=CC=C2N1CCCN3CCN(CC3)C(C4=CC=CC=C4)C5=CC=CC=C5

Molecular Formula

C27H30N4O

Molecular Weight

426.55

References & Citations

[1] Kazuki Yoshida, et al. P2X7 receptor antagonist activity of the anti-allergic agent oxatomide. Eur J Pharmacol. 2015 Nov 15;767:41-51.|[2]K Ohmori, et al. Pharmacological studies on oxatomide (KW-4354) . (7) Antagonistic effects on chemical mediators. Nihon Yakurigaku Zasshi. 1983 May;81 (5) :399-409.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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