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5MP-Propargyl

5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP) . 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation[1]. 5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2100286-15-3

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5mp-propargyl.html

Solubility

10 mM in DMSO

Smiles

O=C(C=C1)N(CC#C)C1=C

Molecular Formula

C8H7NO

Molecular Weight

133.15

References & Citations

[1]Yingqian Zhang, et al. Thiol Specific and Tracelessly Removable Bioconjugation via Michael Addition to 5-Methylene Pyrrolones. J Am Chem Soc. 2017 May 3;139 (17) :6146-6151.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Frequently Asked Questions

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