Norbergenin

Norbergenin, the O-demethyl derivative of bergenin, shows moderate antioxidant activity (IC50 13 μM in DPPH radical scavenging; 32 μM in superoxide anion scavenging) [1].

Product Specifications

CAS Number

[79595-97-4]

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/norbergenin.html

Purity

98.31

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

OC1=C2[C@@]3([H])[C@@](OC(C2=CC(O)=C1O)=O)([H])[C@H]([C@@H]([C@H](O3)CO)O)O

Molecular Formula

C13H14O9

Molecular Weight

314.24

References & Citations

[1]Takahashi H, et al. Synthesis and neuroprotective activity of bergenin derivatives with antioxidant activity. Bioorg Med Chem. 2003;11 (8) :1781-1788.