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Mianserin-d3 (hydrochloride)

Mianserin-d3 (hydrochloride) is the deuterium labeled Mianserin hydrochloride. Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant.

Product Specifications

CAS Number

[1219804-97-3]

Product Name Alternative

Org GB 94-d3

UNSPSC

12352005

Target

Histamine Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling; Others

Field of Research

Neurological Disease; Endocrinology

Purity

97.51

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])N1CC2N(CC1)C3=CC=CC=C3CC4=CC=CC=C42.Cl

Molecular Formula

C18H18D3ClN2

Molecular Weight

303.84

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Olianas MC, et al. The atypical antidepressant mianserin exhibits agonist activity at κ-opioid receptors. Br J Pharmacol. 2012 Nov;167 (6) :1329-41.|[3]Roeder T. High-affinity antagonists of the locust neuronal octopamine receptor. Eur J Pharmacol. 1990 Nov 27;191 (2) :221-4.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

H1 Receptor

Available Sizes

Curated Selection

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