Dehydroandrographolide
Product Specifications
CAS Number
134418-28-3
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Dehydroandrographolide.html
Purity
99.93
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
C[C@@]([C@H]1C/C=C(C=CO2)/C2=O)(CC[C@H]3O)[C@@](CCC1=C)([H])[C@]3(C)CO
Molecular Weight
332.43
References & Citations
[1]Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6.|[2]Chao WW, et al. Isolation and identification of bioactive compounds in Andrographis paniculata (Chuanxinlian). Chin Med. 2010 May 13;5:17.|[3]Basak A, et al. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters. Biochem J. 1999 Feb 15;338 ( Pt 1):107-13.|[4]Zhu T, et al. Dehydroandrographolide succinate inhibits oxidative stress in mice with lipopolysaccharide-induced acute lung injury by inactivating iNOS. Nan Fang Yi Ke Da Xue Xue Bao. 2012 Sep;32(9):1238-41.|[5]Chen H, et al. Synthesis, structure-activity relationships and biological evaluation of dehydroandrographolide and andrographolide derivatives as novel anti-hepatitis B virus agents. Bioorg Med Chem Lett. 2014 May 15;24(10):2353-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Clinical Information
Launched
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