Guanylyl imidodiphosphate (lithium)

Guanylyl imidodiphosphate (Gpp (NH) p) lithium, a non-hydrolyzable GTP analogue, increases adenylate cyclase activity[1][2].

Product Specifications

CAS Number

[64564-03-0]

Product Name Alternative

Gpp (NH) p (lithium)

UNSPSC

12352005

Target

Adenylate Cyclase

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/guanylyl-imidodiphosphate-lithium.html

Purity

98.0

Solubility

H2O : ≥ 50 mg/mL

Smiles

O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](N[P](O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)([H])N2C(NC(N)=NC3=O)=C3N=C2

Molecular Formula

C10H13Li4N6O13P3

Molecular Weight

545.93

References & Citations

[1]B J Terry, et al. Assembly and disassembly properties of microtubules formed in the presence of GTP, 5'-guanylyl imidodiphosphate, and 5'-guanylyl methylenediphosphate. J Biol Chem. 1980 Nov 10;255 (21) :10532-6.|[2]H Abou-Issa, et al. Modulation of follicle-stimulating hormone-sensitive rat testicular adenylate cyclase activity by guanyl nucleotides. Endocrinology. 1979 Jan;104 (1) :189-93.