Norbormide

Norbormide, a rodenticide, is a calcium entry blocker with a selective vasoconstrictor activity. Norbormide shows species- and tissue-specific, endothelium independent, and is restricted to the peripheral arteries of rat[1].

Product Specifications

CAS Number

[991-42-4]

UNSPSC

12352005

Hazard Statement

H302

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/norbormide.html

Purity

98.91

Solubility

10 mM in DMSO

Smiles

OC(C1=CC=CC=C1)(C2=CC=CC=N2)C3=CC4/C(C3[C@H](C(N5)=O)[C@@H]4C5=O)=C(C6=CC=CC=N6)/C7=CC=CC=C7

Molecular Formula

C33H25N3O3

Molecular Weight

511.57

Precautions

H302

References & Citations

[1]Bova S, et al. Norbormide: a calcium entry blocker with selective vasoconstrictor activity in rat peripheral arteries. Cardiovasc Drug Rev. 2001 Fall;19 (3) :226-33.