Phospho-AKT1 (Ser473+Tyr474) Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[AKT1]

NCBI Gene ID

207

Reactivity

Human, Mouse, Rat<br>Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (88%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (100%)

Storage Conditions

Store at -20 degree C. Stable for 12 months from date of receipt.

Specificity

Phospho-AKT1 (Ser473+Tyr474) Antibody detects endogenous levels of AKT1 only when phosphorylated at Ser473+Tyr474.<br>Tissue Specificity: Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lympHnode metastatic (LNMM) stages.

Other Gene Names

[AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha]

Short Name

[AKT1]

Other Product Names

[RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; PKB alpha; RAC-PK-alpha; proto-oncogene c-Akt; protein kinase B alpha; rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha]