Phospho-AKT1 (Ser473+Tyr474) Antibody
Product Specifications
Gene Name
[AKT1]
NCBI Gene ID
207
Reactivity
Human, Mouse, Rat<br>Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (88%), Horse (100%), Dog (100%), Chicken (100%), Xenopus (100%)
Storage Conditions
Store at -20 degree C. Stable for 12 months from date of receipt.
Specificity
Phospho-AKT1 (Ser473+Tyr474) Antibody detects endogenous levels of AKT1 only when phosphorylated at Ser473+Tyr474.<br>Tissue Specificity: Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lympHnode metastatic (LNMM) stages.
Other Gene Names
[AKT1; AKT1; AKT; PKB; RAC; CWS6; PRKBA; PKB-ALPHA; RAC-ALPHA; PKB; RAC; PKB; PKB alpha]
Short Name
[AKT1]
Other Product Names
[RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; RAC-alpha serine/threonine-protein kinase; PKB alpha; RAC-PK-alpha; proto-oncogene c-Akt; protein kinase B alpha; rac protein kinase alpha; v-akt murine thymoma viral oncogene homolog 1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha]
NCBI GI Number
62241013
NCBI Accession Number
NP_001014431.1
NCBI GB Accession Number
NM_001014431.1
Uniprot Accession Number
P31749
CAS Number
9007-83-4
Available Sizes
Curated Selection
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