Phospho-BRK (Tyr342) Antibody
Product Specifications
Gene Name
[BRK]
NCBI Gene ID
5753
Reactivity
Human, Mouse, Rat<br>Predicted Reactivity: Bovine (83%), Sheep (83%)
Storage Conditions
Store at -20 degree C. Stable for 12 months from date of receipt.
Specificity
Phospho-BRK (Tyr342) Antibody detects endogenous levels of BRK only when phosphorylated at Tyr342.<br>Tissue Specificity: Epithelia-specific. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. Not expressed in breast or ovarian tissue but expressed in high percentage of breast and ovarian cancers. Also overexpressed in some metastatic melanomas, lymphomas, colon cancers, squamous cell carcinomas and prostate cancers. Also found in melanocytes. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform 2 is present in prostate epithelial cell lines derived from normal prostate and prostate adenocarcinomas, as well as in a variety of cell lines.
Other Gene Names
[PTK6; PTK6; BRK; BRK]
Short Name
[BRK]
Other Product Names
[protein-tyrosine kinase 6 isoform 2; Protein-tyrosine kinase 6; protein-tyrosine kinase 6; breast tumor kinase; protein-tyrosine kinase BRK; tyrosine-protein kinase BRK; PTK6 protein tyrosine kinase 6; protein tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK]
NCBI GI Number
373432692
NCBI Accession Number
NP_001243287.1
NCBI GB Accession Number
NM_001256358.1
Uniprot Accession Number
Q13882
CAS Number
9007-83-4
Available Sizes
Curated Selection
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