Phospho-NFAT2 (Ser294) Antibody

Phospho-NFAT2 (Ser294) Antibody detects endogenous levels of NFAT2 only when phosphorylated at Ser294.<br>Tissue Specificity: Expressed in thymus, peripheral leukocytes as T-cells and spleen. Isoforms A are preferentially expressed in effector T-cells (thymus and peripheral leukocytes) whereas isoforms B and isoforms C are preferentially expressed in naive T-cells (spleen). Isoforms B are expressed in naive T-cells after first antigen exposure and isoforms A are expressed in effector T-cells after second antigen exposure. Isoforms IA are widely expressed but not detected in liver nor pancreas, neural expression is strongest in corpus callosum. Isoforms IB are expressed mostly in muscle, cerebellum, placenta and thymus, neural expression in fetal and adult brain, strongest in corpus callosum.

[Nuclear factor of activated T-cells, cytoplasmic 1; Nuclear factor of activated T-cells, cytoplasmic 1; nuclear factor of activated T-cells, cytoplasmic 1; NFAT transcription complex cytosolic component; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; NFAT transcription complex cytosolic component; NF-ATc; NFATc]