AIRE Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
[AIRE]
NCBI Gene ID
326
Reactivity
Human
Storage Conditions
Store at -20 degree C. Stable for 12 months from date of receipt.
Specificity
AIRE Antibody detects endogenous levels of total AIRE.<br>Tissue Specificity: Widely expressed. Expressed at higher level in thymus (medullary epithelial cells and monocyte-dendritic cells), pancreas, adrenal cortex and testis. Expressed at lower level in the spleen, fetal liver and lympHnodes. In secondary lymphoid organs, expressed in a discrete population of bone marrow-derived toleregenic antigen presenting cells (APCs) called extrathymic AIRE expressing cells (eTAC) (at protein level). Isoform 2 and isoform 3 seem to be less frequently expressed than isoform 1, if at all.
Other Gene Names
[AIRE; AIRE; APS1; APSI; PGA1; AIRE1; APECED; APECED; APECED protein]
Short Name
[AIRE]
Other Product Names
[autoimmune regulator; Autoimmune regulator; autoimmune regulator; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein]
NCBI GI Number
4557291
NCBI Accession Number
NP_000374.1
NCBI GB Accession Number
NM_000383.3
Uniprot Accession Number
O43918
Available Sizes
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