Catenin-1 Antibody

Catenin-1 Antibody detects endogenous levels of total Catenin-1.<br>Tissue Specificity: Expressed in vascular endothelium. Melanocytes and melanoma cells primarily express the long isoform 1A, whereas keratinocytes express shorter isoforms, especially 3A. The shortest isoform 4A, is detected in normal keratinocytes and melanocytes, and generally lost from cells derived from squamous cell carcinomas or melanomas. The C-terminal alternatively spliced exon B is present in the p120ctn transcripts in the colon, intestine and prostate, but lost in several tumor tissues derived from these organs.

[catenin delta-1 isoform 1ABC; Catenin delta-1; catenin delta-1; p120 catenin; cadherin-associated Src substrate; catenin (cadherin-associated protein), delta 1; Cadherin-associated Src substrate; CAS; p120 catenin; p120(ctn); p120(cas)]