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CaMKK2-IN-1

CaMKK2-IN-1 is a selective, ligand-efficient inhibitor of CaMKK2, with IC50 of 7 nM[1].

Product Specifications

CAS Number

3032691-65-6

UNSPSC

12352005

Target

Calmodulin

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/camkk2-in-1.html

Concentration

10mM

Purity

98.77

Solubility

DMSO : 40 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCOC1=CC=C(C(C2=CC(C3CCCC3)=C(C(O)=O)C=C2)=NC=N4)C4=C1

Molecular Formula

C22H22N2O3

Molecular Weight

362.42

References & Citations

[1]Young Chen, et al. Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2) . J Med Chem. 2023 Dec 14;66 (23) :15750-15760.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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